Description

2-Azetidinecarboxamide,1-(2-Propenyl)-,(S)-(9Ci) is a high-value, chiral azetidine derivative, a crucial building block in modern synthetic organic chemistry. Its significance lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, essential for developing novel active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring constrained, nitrogen-containing heterocycles. Its specific stereochemistry and functional groups make it a versatile synthon for medicinal chemistry and advanced material science applications.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in protease inhibitor and neurological disorder research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new pharmacophores and improve drug potency and selectivity.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Peptidomimetic Development: Incorporated into peptide analogs to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and biological pathways.
• Agrochemical Research: Potential intermediate in the development of new, targeted pesticides and herbicides.

Basic Information

Product Name	2-Azetidinecarboxamide,1-(2-Propenyl)-,(S)-(9Ci)
CAS No.	205443-28-3
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	(S)-1-Allylazetidine-2-carboxamide; 1-Allyl-2-azetidinecarboxamide, (S)-; (2S)-1-(2-Propen-1-yl)-2-azetidinecarboxamide; (S)-1-(Prop-2-en-1-yl)azetidine-2-carboxamide; Azetidine-2-carboxamide, 1-(2-propenyl)-, (S)-; 205443-28-3; (S)-1-Allyl-azetidine-2-carboxylic acid amide
EINECS	Contact for details

Quality Control

Our 2-Azetidinecarboxamide,1-(2-Propenyl)-,(S)-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.