Description

Boc-L-4-Carbamoylphe CAS NO 205126-71-2 is a protected amino acid derivative, specifically the tert-butoxycarbonyl (Boc) derivative of L-4-carbamoylphenylalanine. This compound serves as a crucial, high-purity building block in the synthesis of complex peptides and peptidomimetics, enabling precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for developing therapeutic peptides and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key raw material in the synthesis of novel peptide-based active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected amino acid to incorporate the 4-carbamoylphenylalanine residue.
• Drug Discovery Research: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the development of peptidomimetics.
• Bioconjugation: Acts as a precursor for creating linkers or modified amino acids used in antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Utilized in the synthesis of labeled or tagged peptides for biochemical and cellular studies.

Basic Information

Product Name	Boc-L-4-Carbamoylphe
CAS No.	205126-71-2
Molecular Formula	C₁₅H₂₀N₂O₅
Molecular Weight	308.33 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-4-carbamoylphenylalanine; Boc-4-Carbamoyl-L-phenylalanine; Boc-L-4-Carbamoylphenylalanine; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-(4-carbamoylphenyl)propanoic acid; N-Boc-4-Carbamoyl-L-phenylalanine; Boc-Cpa-OH; Boc-L-Phe(4-CONH2)-OH; tert-Butyloxycarbonyl-L-4-carbamoylphenylalanine
EINECS	Contact for details

Quality Control

Our Boc-L-4-Carbamoylphe is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Specific Rotation	-15.0° to -20.0° (c=1 in DMF)
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.