Description

2-(Neopentyloxycarbonyl)-5-(Trifluoromethyl)Phenylboronic Acid is a high-value, synthetically versatile organoboron building block. This compound is critical for modern cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for constructing biaryl scaffolds found in drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific fluorinated aromatic structures.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials and liquid crystals.
• Chemical Biology & Proteomics: Employed in the development of chemical probes and bioconjugation tools.
• Custom Synthesis & Contract Manufacturing: Essential for fine chemical manufacturers producing bespoke, high-complexity molecules for clients.

Basic Information

Item	Details
Product Name	2-(Neopentyloxycarbonyl)-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	204981-49-7
Molecular Formula	C14H16BF3O4
Molecular Weight	316.09 g/mol
Synonyms	[2-[(2,2-Dimethylpropanoyl)oxy]carbonyl]-4-(trifluoromethyl)benzeneboronic Acid; 2-(Neopentyloxycarbonyl)-5-(Trifluoromethyl)Benzeneboronic Acid; 5-Trifluoromethyl-2-neopentyloxycarbonylphenylboronic Acid; 2-Carboxy-4-trifluoromethylphenylboronic Acid Neopentyl Ester; Boronic Acid, B-[2-[(2,2-dimethyl-1-oxopropoxy)carbonyl]-4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Every batch of 2-(Neopentyloxycarbonyl)-5-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. A Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), identity, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.