Description

1-Bromo-3,5-dimethoxy-4-fluorobenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for selective functionalization and the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments engaged in the development of pharmaceuticals, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and bromine atoms contribute to biological activity.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating novel fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of high-performance, fluorinated polymers with unique thermal and chemical resistance properties.
• Chemical Research & Development: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution in academic and industrial labs.

Basic Information

Item	Detail
Product Name	1-Bromo-3,5-Dimethoxy-4-Fluorobenzene
CAS No.	204654-94-4
Molecular Formula	C8H8BrFO2
Molecular Weight	235.05 g/mol
Synonyms	4-Fluoro-3,5-dimethoxybromobenzene; 3,5-Dimethoxy-4-fluorobromobenzene; 1-Bromo-4-fluoro-3,5-dimethoxybenzene; 4-Fluoro-1-bromo-3,5-dimethoxybenzene; 2-Bromo-1,3-dimethoxy-5-fluorobenzene; 5-Bromo-1,3-dimethoxy-2-fluorobenzene; Benzene, 1-bromo-3,5-dimethoxy-4-fluoro-
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-3,5-dimethoxy-4-fluorobenzene is produced and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including GC, HPLC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.