Description

2-(Dihydro-2H-Thiopyran-4(3H)-Ylidene)Acetonitrile is a versatile heterocyclic nitrile building block featuring a reactive exocyclic double bond. This compound matters as a key synthon in advanced organic synthesis, enabling the construction of complex sulfur-containing heterocycles and functionalized molecular scaffolds. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those containing thiopyran or dihydrothiopyran motifs with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive site for creating diverse chemical libraries.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials due to its conjugated system.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems, where the nitrile and alkene groups offer handles for further modification.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including cycloaddition reactions and catalysis studies.

Basic Information

Product Name	2-(Dihydro-2H-Thiopyran-4(3H)-Ylidene)Acetonitrile
CAS No.	204651-42-3
Molecular Formula	C7H9NS
Molecular Weight	139.22 g/mol
Synonyms	4-(Cyanomethylene)tetrahydro-2H-thiopyran; 2H-Thiopyran-4(3H)-acetonitrile, dihydro-2-(methylene)-; Tetrahydro-2H-thiopyran-4-ylideneacetonitrile; 4-(Cyanomethylene)perhydro-2H-thiopyran; 2-(3,4-Dihydro-2H-thiopyran-4-ylidene)acetonitrile; 4-(Cyanomethylene)thiacyclohexane
EINECS	Contact for details

Quality Control

Our 2-(Dihydro-2H-Thiopyran-4(3H)-Ylidene)Acetonitrile is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.