Description

(Tetrahydro-4H-Pyran-4-Ylidene)Acetonitrile is a versatile nitrile-functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring a reactive exocyclic double bond adjacent to the nitrile group, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediates: Serves as a key synthon in the synthesis of complex heterocyclic compounds and potential drug candidates.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its reactive scaffold.
• Material Science: Acts as a monomer or cross-linking agent in the research of specialty polymers and functional materials.
• Organic Synthesis: Employed in Diels-Alder reactions, Michael additions, and cyclization reactions to build complex ring systems.
• Chemical Biology: Utilized as a probe or linker molecule in bioconjugation and the study of biological pathways.
• Catalyst Ligand Synthesis: Provides a framework for developing novel chiral ligands used in asymmetric catalysis.

Basic Information

Product Name	(Tetrahydro-4H-Pyran-4-Ylidene)Acetonitrile
CAS No.	204651-40-1
Molecular Formula	C7H9NO
Molecular Weight	123.15 g/mol
Synonyms	4-(Cyanomethylene)tetrahydropyran; 4-(Cyanomethylene)oxane; Tetrahydro-4H-pyran-4-ylideneacetonitrile; 4-(Cyanomethylene)tetrahydro-2H-pyran; 2H-Pyran, tetrahydro-4-(cyanomethylene)-; 4-(Cyanomethylene)tetrahydropyran-4-carbonitrile (tautomeric form); 4-Methylenetetrahydropyran-4-carbonitrile
EINECS	Contact for details

Quality Control

Our (Tetrahydro-4H-Pyran-4-Ylidene)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.