Description

Tecadenoson CAS NO 204512-90-3 is a highly selective A1 adenosine receptor agonist, representing a significant class of compounds in cardiovascular and neurological research. Its primary value lies in its potent and specific pharmacological activity, which makes it a critical reference standard and a key intermediate in the development of novel therapeutic agents. This compound is essential for pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) focused on cardioprotection, anti-arrhythmic, and neuroprotective applications.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for analytical method development, validation, and quality control in API manufacturing.
• Cardiovascular Research: A key tool compound for studying A1 adenosine receptor-mediated effects, including heart rate reduction, anti-arrhythmic activity, and ischemic preconditioning.
• Neurological Research: Investigated for its potential neuroprotective effects in models of stroke, epilepsy, and neurodegenerative diseases.
• Intermediate for API Synthesis: Serves as a crucial building block in the multi-step synthesis of advanced drug candidates targeting adenosine receptors.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) and binding assays to discover and characterize new receptor modulators.
• Preclinical Studies: Utilized in animal models to evaluate pharmacokinetics, pharmacodynamics, and efficacy of adenosine-based therapies.

Basic Information

Product Name	Tecadenoson
CAS No.	204512-90-3
Molecular Formula	C19H26N6O3
Molecular Weight	386.45 g/mol
Synonyms	CVT-510; 2-[(6-Amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl)amino]-N-[2-(3,4,5-trimethoxyphenyl)ethyl]acetamide; (2R,3R,4S,5S)-2-[6-Amino-2-[[2-[2-(3,4,5-trimethoxyphenyl)ethylamino]-2-oxoethyl]amino]purin-9-yl]-5-(ethylcarbamoyl)oxolane-3,4-diol; Adenosine A1 Receptor Agonist CVT-510
EINECS	Contact for details

Quality Control

Our Tecadenoson is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) detailing all specifications to ensure compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.