Description

Testosterone-1,2-D2 is a deuterium-labeled analog of the primary male sex hormone, testosterone, specifically labeled at the 1 and 2 positions. This high-purity stable isotope-labeled compound is essential for use as an internal standard in mass spectrometry-based analytical methods, ensuring unparalleled accuracy and reliability in quantitative bioanalysis. It is critically needed by pharmaceutical R&D laboratories, clinical research organizations, and forensic toxicology labs for pharmacokinetic studies, doping control, and hormone level monitoring.

Application

• Internal Standard for LC-MS/MS: Primary application as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for the precise measurement of endogenous testosterone levels.
• Pharmaceutical Development & Bioanalysis: Used in drug metabolism and pharmacokinetics (DMPK) studies for testosterone-based therapies or drugs affecting the endocrine system.
• Clinical Research & Diagnostics: Enables accurate quantification of testosterone in human serum, plasma, and other biological matrices for diagnostic and research purposes.
• Sports Doping Control: A critical tool for anti-doping laboratories worldwide for the definitive identification and quantification of testosterone and its metabolites.
• Endocrinology Studies: Supports research into androgen metabolism, hormone-related disorders, and the development of related biomarkers.
• Forensic Toxicology: Employed in forensic analyses for cases involving anabolic steroid abuse or hormone manipulation.
• Method Development & Validation: Serves as a key component in developing, validating, and ensuring the compliance of analytical methods (e.g., following FDA, EMA guidelines).

Basic Information

Product Name	Testosterone-1,2-D2
CAS No.	204244-83-7
Molecular Formula	C19H26D2O2
Molecular Weight	290.45 g/mol
Synonyms	17β-Hydroxyandrost-4-en-3-one-1,2-d2; (8R,9S,10R,13S,14S,17S)-17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one-1,2-d2; Androst-4-en-17β-ol-3-one-1,2-d2; Testosterone-d2 (1,2); Deuterated Testosterone; [1,2-2H2]-Testosterone
EINECS	Contact for details

Quality Control

Every batch of Testosterone-1,2-D2 is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high chemical and isotopic purity to meet the exacting requirements of analytical reference standards. A detailed Certificate of Analysis (COA), providing data on assay, isotopic enrichment, and impurity profiles (typically by HPLC, NMR, and MS), is supplied with each product and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider storage under an inert atmosphere in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.