Description

3,4'-Bis(Trifluoromethyl)Benzhydrol is a high-value fluorinated organic intermediate characterized by its benzhydrol core flanked by two trifluoromethyl groups. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the introduction of fluorine atoms is key to modulating properties like metabolic stability, lipophilicity, and chemical resistance. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries seeking to incorporate trifluoromethylated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring enhanced bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the trifluoromethyl groups contribute to improved biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials, enhancing thermal stability and electro-optical properties.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart desirable characteristics such as chemical resistance, low surface energy, and improved weatherability.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and as a scaffold for constructing complex, fluorinated aromatic structures in academic and industrial research.
• Advanced Material Research: Explored for use in the development of porous materials (MOFs/COFs) and coatings that benefit from fluorine's unique properties.

Basic Information

Product Name	3,4'-Bis(Trifluoromethyl)Benzhydrol
CAS No.	203915-48-4
Molecular Formula	C₁₆H₁₀F₆O
Molecular Weight	332.24 g/mol
Synonyms	[3,4-Bis(trifluoromethyl)phenyl][4-(trifluoromethyl)phenyl]methanol; α-[3,4-Bis(trifluoromethyl)phenyl]-4-(trifluoromethyl)benzenemethanol; Benzhydrol, 3,4'-bis(trifluoromethyl)-; 3,4'-Di(trifluoromethyl)benzhydrol; (3,4-Bis(trifluoromethyl)phenyl)(4-(trifluoromethyl)phenyl)methanol; 1-(3,4-Bis(trifluoromethyl)phenyl)-1-(4-(trifluoromethyl)phenyl)methanol
EINECS	Contact for details

Quality Control

Our 3,4'-Bis(Trifluoromethyl)Benzhydrol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and quality assurance for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). As a fluorinated organic compound, it should be kept away from strong oxidizing agents and under an inert atmosphere if long-term stability is a concern.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.