Description

Fmoc-(S)-3-Amino-2-Benzylpropanoic Acid CAS NO 203854-62-0 is a high-purity, non-natural amino acid derivative featuring an Fmoc-protected amine group and a free carboxylic acid. This compound is a critical chiral building block for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel therapeutic agents, including enzyme inhibitors and receptor modulators.

Application

• Peptide Synthesis: A key chiral intermediate for the controlled introduction of a constrained, non-proteinogenic amino acid residue into peptide chains.
• Pharmaceutical Research: Used in the development of peptide-based drug candidates, particularly for creating molecules with enhanced metabolic stability and target specificity.
• Combinatorial Chemistry: Serves as a valuable building block in libraries for high-throughput screening to identify new bioactive compounds.
• Bioconjugation: The free carboxylic acid group enables coupling to other molecules, carriers, or surfaces for creating labeled probes or biomaterials.
• Academic Research: Employed in studies of peptide structure-activity relationships (SAR) and the synthesis of model compounds for biochemical assays.

Basic Information

Product Name	Fmoc-(S)-3-Amino-2-Benzylpropanoic Acid
CAS No.	203854-62-0
Molecular Formula	C26H25NO4
Molecular Weight	415.48 g/mol
Synonyms	Fmoc-(S)-3-Amino-2-benzylpropionic Acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-amino-2-benzylpropanoic Acid; Fmoc-3-Amino-2-benzylpropanoic Acid; Fmoc-Abz-OH; (S)-2-Benzyl-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoic Acid; Nα-Fmoc-3-amino-2-benzylpropanoic acid; Fmoc-3-Abz-OH
EINECS	Contact for details

Quality Control

Our Fmoc-(S)-3-Amino-2-Benzylpropanoic Acid is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.