Description

Secalciferol 24-Glucuronide is a key conjugated metabolite of vitamin D, specifically of secalciferol (24,25-dihydroxyvitamin D3). This compound is of significant importance in biochemical research and pharmaceutical development for studying vitamin D metabolism and its regulatory pathways. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in metabolic studies, biomarker analysis, and the development of reference standards for clinical assays.

Application

• Biochemical Research: Used as a critical reference standard and reagent in studies investigating the metabolic pathways and biological activity of vitamin D analogs.
• Diagnostic Development: Serves as a calibration standard in the development and validation of immunoassays and LC-MS/MS methods for quantifying vitamin D metabolites in biological samples.
• Pharmaceutical R&D: Employed in pharmacokinetic and pharmacodynamic studies to understand the disposition and conjugation of secalciferol and related compounds.
• Metabolite Identification: Essential for the structural confirmation and quantification of vitamin D metabolites in drug metabolism and toxicology studies.
• Academic Studies: Utilized in university and institutional research focused on endocrinology, bone health, and calcium homeostasis.

Basic Information

Product Name	Secalciferol 24-Glucuronide
CAS No.	203737-01-3
Molecular Formula	C30H48O9
Molecular Weight	552.70 g/mol
Synonyms	24,25-Dihydroxyvitamin D3 24-Glucuronide; 24R,25-Dihydroxycholecalciferol 24-Glucuronide; (24R)-24,25-Dihydroxyvitamin D3 24-Glucuronide; Secalciferol Glucuronide; 24-Glucuronyl-24,25-dihydroxyvitamin D3; Vitamin D3 metabolite 24-glucuronide
EINECS	Contact for details

Quality Control

Our Secalciferol 24-Glucuronide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with research-grade standards. Custom synthesis and purification to meet specific project requirements are available.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.