Description

2-(3,4-Dihydroxyphenyl)Ethyl-1,1,2,2-D4-Amine Hcl is a deuterated isotopologue of dopamine hydrochloride, where four hydrogen atoms on the ethylamine side chain are replaced with deuterium. This compound is crucial for advanced research and development, providing a stable, non-radioactive isotopic label for tracing, metabolic studies, and analytical method development. It is primarily utilized by pharmaceutical researchers, analytical chemists, and manufacturers of reference standards in the life sciences sector.

Application

• Internal Standard for LC-MS/MS Analysis: Serves as a critical quantitative reference in bioanalytical assays for neurotransmitters and their metabolites.
• Metabolic Pathway Tracing: Used in pharmacokinetic (PK) and pharmacodynamic (PD) studies to track the fate of dopamine and related compounds without radioactive hazards.
• Deuterated Reference Material: Essential for calibrating mass spectrometers and validating analytical methods in clinical and forensic toxicology.
• Neuroscience Research: A key tool for investigating dopaminergic systems, receptor binding studies, and the biochemistry of neurological disorders.
• Pharmaceutical Impurity Profiling: Assists in the identification and quantification of deuterated drug metabolites during development.
• Stable Isotope Labeled Compound Synthesis: Acts as a building block for synthesizing more complex labeled molecules for research.

Basic Information

Product Name	2-(3,4-Dihydroxyphenyl)Ethyl-1,1,2,2-D4-Amine Hcl
CAS No.	203633-19-6
Molecular Formula	C8H7D4ClNO2
Molecular Weight	189.67 g/mol
Synonyms	Dopamine-d4 Hydrochloride; 4-(2-Aminoethyl)-1,2-benzenediol-1,1,2,2-d4 Hydrochloride; 2-(3,4-Dihydroxyphenyl)ethyl-1,1,2,2-d4-amine hydrochloride; 3,4-Dihydroxyphenethylamine-d4 HCl; 3-Hydroxytyramine-d4 Hydrochloride; DA-d4 HCl; (2,2,3,3-D4)-Dopamine Hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dihydroxyphenyl)Ethyl-1,1,2,2-D4-Amine Hcl is manufactured under strict quality systems to ensure high isotopic and chemical purity suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profiles. We adhere to relevant standards for research chemicals and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.