Description

2,4,6-Trifluoro-1-n-Propoxybenzene is a high-purity fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its value lies in its unique trifluoromethyl-substituted aromatic structure, which imparts desirable electronic and steric properties to target molecules. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery, particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving charge transport and thermal stability.
• Polymer Modification: Incorporated as a monomer or additive to create specialty polymers with enhanced chemical resistance, lower dielectric constants, and improved weatherability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce the propoxy-trifluorophenyl moiety.
• Chemical Research & Development: Essential for academic and industrial research exploring new fluorination methodologies and the properties of fluorine-containing aromatics.

Basic Information

Product Name	2,4,6-Trifluoro-1-n-Propoxybenzene
CAS No.	203511-24-4
Molecular Formula	C9H9F3O
Molecular Weight	190.16 g/mol
Synonyms	1-Propoxy-2,4,6-trifluorobenzene; 2,4,6-Trifluorophenyl propyl ether; n-Propyl 2,4,6-trifluorophenyl ether; Benzene, 2,4,6-trifluoro-1-propoxy-; 2,4,6-Trifluoro-1-propoxybenzene; 2,4,6-Trifluorophenoxypropane
EINECS	Contact for details

Quality Control

Every batch of 2,4,6-Trifluoro-1-n-Propoxybenzene is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards, and our specifications are designed to meet the rigorous demands of research and commercial synthesis. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles as determined by GC, HPLC, and NMR, is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.