Description

2-Cyano-3-(2-Hydroxyphenyl)Acrylamide is a specialized acrylamide derivative featuring a cyano group and a phenolic hydroxyl group, making it a versatile intermediate for advanced organic synthesis. This compound matters for its role as a key building block in the development of functional molecules with specific electronic and binding properties. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly those targeting enzymes or receptors where the phenolic and acrylamide motifs are pharmacologically relevant.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or plant growth regulators, leveraging its molecular scaffold for bioactivity.
• Organic Electronic Materials: Acts as a building block for conjugated polymers or small molecules used in organic light-emitting diodes (OLEDs) or sensors due to its electron-withdrawing cyano group and potential for polymerization.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies, such as cycloaddition reactions or as a ligand precursor in coordination chemistry.
• Dye & Pigment Intermediate: Utilized in the synthesis of advanced dyes and pigments where the acrylamide core can contribute to color fastness and molecular stability.
• Cross-linking Agent: Functions as a potential cross-linker in polymer chemistry, where its double bond and functional groups can participate in curing or network formation.

Basic Information

Product Name	2-Cyano-3-(2-Hydroxyphenyl)Acrylamide
CAS No.	203508-98-9
Molecular Formula	C10H8N2O2
Molecular Weight	188.18 g/mol
Synonyms	(2E)-2-Cyano-3-(2-hydroxyphenyl)prop-2-enamide; 2-Propenamide, 2-cyano-3-(2-hydroxyphenyl)-, (2E)-; 2-Cyano-3-(2-hydroxyphenyl)acrylic acid amide; (E)-2-Cyano-3-(2-hydroxyphenyl)acrylamide; o-Hydroxybenzylidenecyanoacetamide; 2-Hydroxybenzylidenecyanoacetamide; NSC 405122; ZINC000005098741
EINECS	Contact for details

Quality Control

Every batch of 2-Cyano-3-(2-Hydroxyphenyl)Acrylamide undergoes rigorous quality testing to ensure compliance with industry standards for purity and identity. Our quality management system is designed to provide traceability and consistency for research and scale-up applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.