Description

Deschloroaripiprazole is a key pharmaceutical intermediate and metabolite of the antipsychotic drug Aripiprazole. This compound is of significant value for research and development in the pharmaceutical industry, particularly in the study of drug metabolism, pharmacokinetics, and the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on neuroscience and psychiatric drug development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis and research of Aripiprazole and its analogs.
• Metabolite Reference Standard: Used as an analytical standard in bioanalytical studies to understand the metabolic pathways and pharmacokinetics of Aripiprazole.
• Research & Development: Essential for preclinical and clinical research focused on central nervous system (CNS) disorders.
• Process Chemistry: Employed in the development and optimization of manufacturing processes for antipsychotic APIs.
• Quality Control: Serves as a high-purity reference material for impurity profiling and assay validation in pharmaceutical quality control laboratories.

Basic Information

Product Name	Deschloroaripiprazole
CAS No.	203395-81-7
Molecular Formula	C23H27N3O2
Molecular Weight	377.48 g/mol
Synonyms	7-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one; Deschloro Aripiprazole; Aripiprazole Impurity; OPC-14597 metabolite; UNII-9K5C8V7C8B; Dechloro Aripiprazole; Aripiprazole Related Compound
EINECS	Contact for details

Quality Control

Our Deschloroaripiprazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods (IR, NMR, MS), to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.