Description

2-Fluoro-5-Methylphenylacetic Acid is a versatile fluorinated aromatic building block of significant importance in modern synthetic chemistry. Its core value lies in its ability to introduce both a phenylacetic acid moiety and a fluorine substituent into target molecules, enabling the fine-tuning of physicochemical properties. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules where the fluorine atom enhances metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the fluorine atom to improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic display technologies.
• Organic Synthesis Building Block: Employed in coupling reactions (e.g., Suzuki, Heck) and as a precursor for amides, esters, and other derivatives in complex molecule assembly.
• Chemical Research & Development: Essential for academic and industrial R&D exploring new fluorination strategies and structure-activity relationships (SAR).

Basic Information

Product Name	2-Fluoro-5-Methylphenylacetic Acid
CAS No.	203314-27-6
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	(2-Fluoro-5-methylphenyl)acetic acid; 2-(2-Fluoro-5-methylphenyl)acetic acid; 5-Methyl-2-fluorophenylacetic acid; α-(2-Fluoro-5-methylphenyl)acetic acid; 2-Fluoro-5-methylbenzeneacetic acid; 2-Fluoro-5-methyl-α-toluic acid; 203314-27-6; Fluoromethylphenylacetic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methylphenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.