Description

3-Chloro-5-Fluoroanisole is a versatile halogenated anisole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for selective functionalization and incorporation into complex molecular architectures. This intermediate is primarily needed by pharmaceutical, agrochemical, and specialty chemical research and development sectors for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Liquid Crystal & OLED Material Precursor: Employed in the manufacture of specialty chemicals for electronic displays and optoelectronic devices.
• Organic Synthesis Building Block: Facilitates cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitutions to construct complex molecules.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and functional pigments.
• Polymer Modifier: Used to introduce specific functional groups into polymer chains to alter material properties.

Basic Information

Product Name	3-Chloro-5-Fluoroanisole
CAS No.	202925-08-4
Molecular Formula	C7H6ClFO
Molecular Weight	160.57 g/mol
Synonyms	1-Chloro-3-fluoro-5-methoxybenzene; 3-Chloro-5-fluoromethoxybenzene; 5-Chloro-3-fluoroanisole; Benzene, 1-chloro-3-fluoro-5-methoxy-; 3-Fluoro-5-chloroanisole; 3-Chloro-5-fluoro-1-methoxybenzene; m-Chloro-m-fluoroanisole
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluoroanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your R&D and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.