Description

2-Chloro-3,5-Dibromo-1-Fluorobenzene is a high-purity halogenated benzene derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for selective functionalization, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), especially in the development of fluorinated drug candidates where the fluorine atom enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the halogen atoms for potent biological activity.
• Material Science Research: Serves as a precursor for liquid crystals, organic semiconductors, and polymers where specific halogen atoms are required to tune electronic and physical properties.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed reactions (e.g., Suzuki, Stille, Negishi) due to the presence of multiple halogen substituents with differing reactivities.
• Fluorine Chemistry: A valuable reagent for studying nucleophilic aromatic substitution (SNAr) and other fluorine-specific transformations in research and development.
• Dye and Pigment Intermediate: Used in the synthesis of complex halogenated dyes and pigments for high-performance applications.

Basic Information

Product Name	2-Chloro-3,5-Dibromo-1-Fluorobenzene
CAS No.	202925-04-0
Molecular Formula	C6H2Br2ClF
Molecular Weight	288.34 g/mol
Synonyms	1-Fluoro-2-chloro-3,5-dibromobenzene; 2-Chloro-3,5-dibromofluorobenzene; 3,5-Dibromo-2-chloro-1-fluorobenzene; Benzene, 2-chloro-3,5-dibromo-1-fluoro-; 2-Chloro-3,5-dibromophenyl fluoride
EINECS	Contact for details

Quality Control

Our 2-Chloro-3,5-Dibromo-1-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.