Description

2-Oxazolidinone, 3-Acetyl-4,5,5-Trimethyl-, (R)- (9Ci) is a high-purity, chiral oxazolidinone derivative, a crucial building block in asymmetric synthesis. Its value lies in its role as a versatile chiral auxiliary and intermediate for constructing complex, stereochemically defined molecules, enabling the production of high-value pharmaceuticals and agrochemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop enantiomerically pure active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for antibiotics and central nervous system (CNS) agents.
• Asymmetric Synthesis Auxiliary: Used as a chiral controller in aldol, alkylation, and Diels-Alder reactions to induce high stereoselectivity.
• Agrochemical Research: Serves as a precursor in developing novel, stereospecific herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Fine Chemical Synthesis: Employed in academic and industrial R&D for constructing complex natural products and specialty chemicals requiring specific stereochemistry.
• Catalyst Ligand Precursor: Can be utilized to develop novel chiral ligands for transition metal catalysis.

Basic Information

Product Name	2-Oxazolidinone, 3-Acetyl-4,5,5-Trimethyl-, (R)- (9Ci)
CAS No.	202920-37-4
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	(R)-3-Acetyl-4,5,5-trimethyl-1,3-oxazolidin-2-one; (R)-3-Acetyl-4,5,5-trimethyloxazolidin-2-one; (4R)-3-Acetyl-4,5,5-trimethyl-1,3-oxazolidin-2-one; (R)-4,5,5-Trimethyl-3-acetyl-2-oxazolidinone; Chiral Evans Auxiliary Derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Oxazolidinone, 3-Acetyl-4,5,5-Trimethyl-, (R)- (9Ci) is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC, NMR, and IR spectroscopy, to ensure high chemical and enantiomeric purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.