Description

4-Bromo-3,5-Difluoroanisole is a halogenated anisole derivative, specifically a bromo-difluoro substituted aromatic ether. This compound serves as a versatile and valuable building block in advanced organic synthesis, particularly for introducing specific halogenated aromatic motifs. It is primarily utilized by pharmaceutical and agrochemical research and development teams for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing halogenated aromatic rings for enhanced bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides where the bromo and difluoro substitutions can influence binding affinity and environmental persistence.
• Liquid Crystal & OLED Material Research: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to construct more complex biaryl structures.
• Functional Material Development: Employed in creating specialized polymers, ligands for catalysis, and other advanced materials requiring precise halogen substitution patterns.

Basic Information

Product Name	4-Bromo-3,5-Difluoroanisole
CAS No.	202865-61-0
Molecular Formula	C7H5BrF2O
Molecular Weight	223.02 g/mol
Synonyms	1-Bromo-2,6-difluoro-4-methoxybenzene; 4-Methoxy-2,6-difluorobromobenzene; Benzene, 1-bromo-2,6-difluoro-4-methoxy-; Anisole, 4-bromo-3,5-difluoro-; 2,6-Difluoro-4-methoxybromobenzene; 4-Bromo-2,6-difluoroanisole
EINECS	Contact for details

Quality Control

Our 4-Bromo-3,5-Difluoroanisole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support development and scale-up needs with custom synthesis and specification tailoring.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed and stored in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.