Description

(S)-2-(Boc-Amino)-1,3-Diphenyl-1-Propanone is a high-purity chiral building block featuring a Boc-protected amino group and a propiophenone backbone. This compound matters as a critical intermediate in the synthesis of complex pharmaceutical molecules, particularly for introducing stereochemistry and functional handles for further derivatization. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and antiviral therapeutic areas.
• Peptidomimetics Synthesis: Used in the construction of non-peptide scaffolds that mimic peptide structure and function, valuable in drug discovery.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to create enantiomerically pure compounds.
• API Development: Integral in the multi-step synthesis of complex, stereochemically defined Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: A requested building block for custom synthesis services catering to pharmaceutical and biotech clients.

Basic Information

Product Name	(S)-2-(Boc-Amino)-1,3-Diphenyl-1-Propanone
CAS No.	202861-97-0
Molecular Formula	C20H23NO3
Molecular Weight	325.40 g/mol
Synonyms	(S)-2-[(tert-Butoxycarbonyl)amino]-1,3-diphenylpropan-1-one; (S)-2-(tert-Butoxycarbonylamino)-1,3-diphenyl-1-propanone; (S)-2-(Boc-amino)-1,3-diphenylpropan-1-one; Boc-L-1,3-Diphenylalanine ketone; (S)-1,3-Diphenyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]propan-1-one; tert-Butyl (S)-(1-oxo-1,3-diphenylpropan-2-yl)carbamate; (S)-2-(Boc-Amino)-1,3-Diphenylpropanone
EINECS	Contact for details

Quality Control

Our (S)-2-(Boc-Amino)-1,3-Diphenyl-1-Propanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.