Description

(2R)-[(Diphenylacetyl)Amino](Phenyl)Acetic Acid is a high-purity chiral building block and pharmaceutical intermediate of significant commercial and research interest. Its value lies in its defined stereochemistry and functional groups, which are critical for the synthesis of enantiomerically pure compounds, particularly in medicinal chemistry. This product is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop or scale up novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Used as a starting material or reagent in stereoselective chemical transformations to construct complex molecular architectures.
• Peptidomimetic Research: Serves as a constrained amino acid analog in the design and synthesis of peptide-like molecules with enhanced stability and bioavailability.
• Catalyst and Ligand Development: Employed in the preparation of novel chiral catalysts or ligands for enantioselective catalysis.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation of related pharmaceutical compounds.
• Academic & Industrial R&D: Fundamental research tool in universities and corporate labs exploring new chemical entities and synthetic methodologies.

Basic Information

Product Name	(2R)-[(Diphenylacetyl)Amino](Phenyl)Acetic Acid
CAS No.	202805-26-3
Molecular Formula	C22H19NO3
Molecular Weight	345.39 g/mol
Synonyms	(R)-2-[(Diphenylacetyl)Amino]-2-Phenylacetic Acid; (R)-N-(Diphenylacetyl)-Phenylglycine; (2R)-2-[(2,2-Diphenylacetyl)Amino]-2-Phenylacetic Acid; (R)-DPA-Phenylglycine; (R)-N-(2,2-Diphenylacetyl)phenylglycine; (R)-α-[(Diphenylacetylamino)]benzeneacetic Acid; UNII-9V2I2F8Q5K; (R)-N-Diphenylacetylphenylglycine
EINECS	Contact for details

Quality Control

Our (2R)-[(Diphenylacetyl)Amino](Phenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.