Description

n-Boc-2-Methylamino-Ethylamine Hcl is a high-purity, protected amine derivative widely used as a critical building block in organic synthesis. This compound matters for its role in introducing a functionalized ethylamine spacer with a Boc-protected secondary amine, enabling precise molecular construction while preventing unwanted side reactions. Pharmaceutical researchers and fine chemical manufacturers need it for the development of active pharmaceutical ingredients (APIs), peptide mimetics, and sophisticated linker molecules in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon for constructing novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Peptide Chemistry: Serves as a backbone modifier or spacer in the synthesis of peptide analogs and conjugates.
• Linker for Bioconjugation: Used in the development of antibody-drug conjugates (ADCs) and other targeted biopharmaceuticals.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection in multi-step synthetic sequences.
• Agrochemical Research: Employed in the synthesis of advanced crop protection agents and herbicides.
• Material Science: Acts as a functional monomer or cross-linking agent in the production of specialty polymers and resins.

Basic Information

Product Name	n-Boc-2-Methylamino-Ethylamine Hcl
CAS No.	202207-79-2
Molecular Formula	C8H19ClN2O2
Molecular Weight	210.70 g/mol
Synonyms	1-Boc-2-(Methylamino)ethylamine hydrochloride; N-(tert-Butoxycarbonyl)-N'-methylethylenediamine hydrochloride; 2-[(tert-Butoxycarbonyl)(methyl)amino]ethylamine hydrochloride; N-Boc-N'-methylethylenediamine hydrochloride; tert-Butyl N-[2-(methylamino)ethyl]carbamate hydrochloride; N1-(tert-Butoxycarbonyl)-N2-methylethane-1,2-diamine hydrochloride; Boc-N-Me-ethylenediamine HCl; 2-(Boc-methylamino)ethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our n-Boc-2-Methylamino-Ethylamine Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.