Description

Pamam Dendrimer, Generation 4.5 Solution is a precisely engineered, half-generation poly(amidoamine) dendrimer with a carboxylic acid surface. This unique branched macromolecule is critical for creating well-defined, nanoscale architectures with a high density of functional surface groups. It is essential for researchers and formulators in advanced material science and nanotechnology who require a consistent, high-purity building block for drug delivery systems, diagnostic agents, and sophisticated polymer composites. The product is supplied as a solution for ease of handling and integration into various synthetic protocols.

Application

• Drug Delivery & Nanomedicine: As a core component for constructing targeted drug delivery vehicles, gene carriers, and contrast agents due to its biocompatibility and modifiable surface.
• Diagnostic Imaging: Functionalization with imaging moieties (e.g., fluorescent dyes, MRI contrast agents) for use in biomedical diagnostics and research.
• Catalyst Support: Serving as a nanoscale scaffold or template for immobilizing metal catalysts, enhancing catalytic activity and selectivity in organic synthesis.
• Surface Modification & Coatings: Modifying material surfaces to alter properties such as wettability, adhesion, or biocompatibility for medical devices and sensors.
• Polymer & Composite Materials: Acting as a cross-linking agent, rheology modifier, or nano-filler to create advanced polymers with tailored mechanical and thermal properties.
• Sensor Technology: Utilization in the fabrication of chemical and biological sensors by attaching specific receptor molecules to the dendrimer surface.

Basic Information

Product Name	Pamam Dendrimer, Generation 4.5 Solution
CAS No.	202009-66-3
Molecular Formula	C622H1248N186O186
Molecular Weight	~14,215 g/mol (Theoretical)
Synonyms	PAMAM Dendrimer, G4.5; Poly(amidoamine) Dendrimer, Generation 4.5, COOH-terminated; Starburst Dendrimer, G4.5; PAMAM G4.5; PAMAM Dendrimer ethylenediamine core, generation 4.5; PAMAM G=4.5 carboxylic acid terminated; Nanoscale dendritic polymer G4.5
EINECS	Contact for details

Quality Control

Our Pamam Dendrimer, Generation 4.5 Solution is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including size-exclusion chromatography (SEC/GPC), nuclear magnetic resonance (NMR), and titration of surface groups, to ensure structural integrity, purity, and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing concentration, solvent, and critical specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. For long-term storage, consider freezing at -20°C under an inert atmosphere. Allow the solution to reach room temperature before opening to prevent condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Concentration	10% w/w in suitable solvent (e.g., Water, Methanol)
Identification (NMR)	Conforms to structure
Purity (SEC)	≥ 95% (Dendrimer content)
Molecular Weight (SEC-MALS)	~14,000 - 15,000 g/mol
Surface Group (COOH) Content	~128 groups per molecule (Theoretical)
Solvent Content	As specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.