Description

3-Chloro-5-Fluorophenylacetic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated structure enables precise molecular modifications. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material Production: Serves as a building block for fluorinated components in electronic display and lighting materials.
• Organic Synthesis & Research: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to create complex biaryl structures in academic and industrial R&D.
• Peptide Mimetics & Bio-conjugation: The acetic acid moiety allows for coupling to create novel peptide analogs and linker molecules for bioconjugation.

Basic Information

Product Name	3-Chloro-5-Fluorophenylacetic Acid
CAS No.	202001-00-1
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	(3-Chloro-5-fluorophenyl)acetic Acid; 2-(3-Chloro-5-fluorophenyl)acetic Acid; 3-Chloro-5-fluorobenzeneacetic Acid; 3-Chloro-5-fluoro-α-toluic Acid; 202001-00-1; 3-Cl-5-F-PhAA; 3,5-Substituted Phenylacetic Acid Derivative
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluorophenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and FTIR to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.