Description

Leucine, n-(Methoxyacetyl)- (9Ci) is a chemically modified derivative of the essential amino acid L-leucine, featuring a methoxyacetyl protecting group. This modification is crucial for its role as a key synthetic intermediate in the production of complex peptides and active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for applications in drug discovery and process development. The compound is supplied with a CAS registry number of 201870-78-2.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Proteomics Research: Used in biochemical research for studying protein structure, function, and enzyme-substrate interactions.
• Drug Discovery: Employed in medicinal chemistry for the design and development of new drug candidates targeting various diseases.
• Bioconjugation: Acts as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Leucine, n-(Methoxyacetyl)- (9Ci)
CAS No.	201870-78-2
Molecular Formula	C9H17NO4
Molecular Weight	203.24 g/mol
Synonyms	N-Methoxyacetylleucine; 2-(Methoxyacetamido)-4-methylpentanoic acid; (S)-2-(2-Methoxyacetamido)-4-methylpentanoic acid; Methoxyacetyl-L-leucine; L-Leucine, N-(methoxyacetyl)-; N-(Methoxyacetyl)-L-leucine; Leucine, N-(methoxyacetyl)-, L-; 201870-78-2
EINECS	Contact for details

Quality Control

Our Leucine, n-(Methoxyacetyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.