Description

H-Gln-Amc HBr is a high-purity, synthetic amino acid derivative used as a critical building block in peptide synthesis and pharmaceutical research. This compound is valued for its role in introducing specific functional groups and modifying peptide backbones to influence biological activity and stability. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in drug discovery and advanced biomaterial production. Consistent quality and reliable supply are essential for the success of downstream R&D and manufacturing processes.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the solid-phase and solution-phase synthesis of novel therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a specialized reagent in enzymatic studies, substrate specificity investigations, and proteomics research.
• Drug Discovery: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the development of enzyme inhibitors or receptor modulators.
• Fine Chemical Synthesis: Acts as a protected glutamine derivative for constructing complex organic molecules and custom peptides for various applications.
• Reference Standard: Suitable for use as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	H-Gln-Amc HBr
CAS No.	201851-47-0
Molecular Formula	C9H16BrN3O3
Molecular Weight	294.15 g/mol
Synonyms	H-Gln-AMC hydrobromide; L-Glutamine-7-amido-4-methylcoumarin hydrobromide; Gln-AMC HBr; H-L-Gln-AMC*HBr; 7-Amido-4-methylcoumarin conjugate of L-glutamine HBr; Fluorogenic glutamine substrate; Glutamine-AMC; AMC-labeled glutamine derivative
EINECS	Contact for details

Quality Control

Our H-Gln-Amc HBr is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.