Description

H-Ala-Afc Tfa is a specialized, high-purity protected amino acid derivative, widely recognized as a critical building block in advanced organic synthesis. Its primary value lies in enabling the precise construction of complex peptides and peptidomimetics, where it serves as a key intermediate for introducing specific functional groups. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of novel therapeutic agents and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial protected intermediate for the sequential assembly of custom peptide sequences in drug discovery and research.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and potential drug candidates targeting various diseases.
• Bioconjugation & Probe Development: Serves as a building block for creating fluorescent or affinity-labeled peptides used in diagnostic assays and cellular imaging.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify new bioactive molecules.
• Academic & Industrial R&D: A fundamental reagent for studying peptide structure-activity relationships and developing new synthetic methodologies.

Basic Information

Product Name	H-Ala-Afc Tfa
CAS No.	201847-57-6
Molecular Formula	C11H13F3N2O5
Molecular Weight	310.23 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-4-(trifluoromethyl)-L-phenylalanine; Fmoc-Ala-Afc(4-CF3)-OH; Fmoc-L-Ala-L-Afc(4-CF3)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-4-(trifluoromethyl)-L-phenylalanine; H-Ala-Afc(4-CF3)-OH (Fmoc protected precursor); Fmoc-Alanine-4-(Trifluoromethyl)phenylalanine; Protected dipeptide Fmoc-Ala-Afc(Tfa)
EINECS	Contact for details

Quality Control

Our H-Ala-Afc Tfa is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.