Description

Bz-Asn-Pna CAS NO 201733-11-1 is a specialized protected amino acid derivative, specifically N-Benzoyl-L-asparagine p-nitroanilide. This compound serves as a critical synthetic intermediate and biochemical tool, valued for its role in peptide synthesis and enzymatic research. It is primarily utilized by research institutions and pharmaceutical development companies engaged in proteomics, enzyme substrate studies, and the synthesis of complex bioactive peptides.

Application

• Enzyme Substrate Development: Used as a chromogenic or fluorogenic substrate for studying the activity of proteases, particularly asparagine-specific endopeptidases.
• Peptide Synthesis Intermediate: Acts as a key building block in solid-phase and solution-phase peptide synthesis, where the protecting groups (Bz and Pna) require specific cleavage conditions.
• Biochemical Research: Employed in mechanistic studies of enzyme kinetics and inhibition, helping to elucidate biological pathways.
• Pharmaceutical R&D: Utilized in the discovery and development stages of novel therapeutic agents targeting specific enzymatic processes.
• Diagnostic Reagent Manufacturing: Serves as a component in the formulation of assay kits for clinical and research diagnostics related to protease activity.

Basic Information

Item	Detail
Product Name	Bz-Asn-Pna
CAS No.	201733-11-1
Molecular Formula	C17H16N4O5
Molecular Weight	356.34 g/mol
Synonyms	N-Benzoyl-L-asparagine p-nitroanilide; L-Asparagine, N2-benzoyl-, 4-nitroanilide; Bz-Asn-pNA; Benzoyl-Asparagine p-Nitroanilide; Asparagine protease substrate; Nα-Benzoyl-L-asparagine 4-nitroanilide; Bz-L-Asn-pNA; N-Benzoyl-L-asparagine 4-nitroanilide
EINECS	Contact for details

Quality Control

Our Bz-Asn-Pna is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, identity confirmation by spectroscopic methods (IR, NMR), and chiral purity assessment. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific research or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% L-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.