Description

D-Glucose-13C6-1 2 3 4 5 6 6-D7 is a highly enriched, isotopically labeled glucose molecule, where all six carbon atoms are the stable isotope carbon-13 and seven hydrogen atoms are deuterium. This compound is essential as a critical internal standard and tracer in quantitative mass spectrometry-based metabolomics and pharmacokinetic studies. It is primarily required by pharmaceutical R&D laboratories, clinical research organizations, and academic institutions conducting advanced metabolic flux analysis, drug metabolism research, and biomarker discovery.

Application

• Quantitative Mass Spectrometry (MS) Internal Standard: Used for the accurate quantification of endogenous glucose and related metabolites in complex biological matrices like plasma, serum, and cell lysates.
• Metabolic Flux Analysis (MFA): Serves as a precise tracer to map and quantify the pathways of central carbon metabolism in live cells, tissues, or whole organisms.
• Drug Metabolism and Pharmacokinetics (DMPK): Employed in stable isotope labeling studies to investigate the absorption, distribution, metabolism, and excretion (ADME) of new chemical entities.
• Clinical Diagnostics & Biomarker Research: Facilitates the development of highly specific and sensitive LC-MS/MS assays for diagnosing metabolic disorders such as diabetes.
• Nutritional Science Research: Used to study glucose uptake, utilization, and turnover in nutritional intervention studies.
• NMR Spectroscopy: Acts as a labeled substrate for 13C-NMR studies to elucidate metabolic pathways and enzyme mechanisms without spectral interference.

Basic Information

Product Name	D-Glucose-13C6-1 2 3 4 5 6 6-D7
CAS No.	201417-01-8
Molecular Formula	13C6D7H5O6
Molecular Weight	193.15 g/mol
Synonyms	D-Glucose-13C6,d7; [U-13C6,1,2,3,4,5,6,6-d7]-D-Glucose; D-Glucose (13C6, 98%; D7, 98%); Fully Labeled 13C6D7-Glucose; Deuterated 13C-Glucose; Isotopic Tracer Glucose; Stable Isotope Labeled Glucose; Metabolic Tracer
EINECS	Contact for details

Quality Control

Every batch of D-Glucose-13C6-1 2 3 4 5 6 6-D7 is manufactured and analyzed under strict quality systems. The product undergoes rigorous testing to ensure compliance with specifications for isotopic enrichment, chemical purity, and absence of interfering impurities. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (Atom % 13C and % D), chemical purity by HPLC, and specific tests is provided with each shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Isotopic Purity (Atom % 13C)	≥ 98%
Isotopic Purity (Atom % D)	≥ 98%
Chemical Purity (HPLC)	≥ 98%
Specific Optical Rotation	+52.5° to +53.5° (c=10 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.