Description

Ac-Dab(Boc)-Oh CAS NO 201351-32-8 is a protected amino acid derivative, specifically N-α-Acetyl-N-δ-(tert-butoxycarbonyl)-L-2,4-diaminobutyric acid, widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity, structurally defined intermediates to ensure the fidelity and yield of complex peptide sequences. It is primarily utilized by the pharmaceutical, biotechnology, and life sciences industries for the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of the diaminobutyric acid (Dab) residue with orthogonal protecting groups.
• Pharmaceutical Research: Building block for the development of peptide-based drugs, including antimicrobial peptides (AMPs) and hormone analogs.
• Bioconjugation: Used to introduce functional handles or labels into peptides and proteins via its side-chain amine after deprotection.
• Combinatorial Chemistry: A valuable reagent in libraries for drug discovery and structure-activity relationship (SAR) studies.
• Biochemical Tool Development: Synthesis of substrates, inhibitors, or probes for enzymatic assays and biological studies.
• Custom Peptide Services: A fundamental raw material for CROs and CDMOs offering bespoke peptide manufacturing.

Basic Information

Product Name	Ac-Dab(Boc)-Oh
CAS No.	201351-32-8
Molecular Formula	C11H20N2O5
Molecular Weight	260.29 g/mol
Synonyms	N-α-Acetyl-N-δ-(tert-butoxycarbonyl)-L-2,4-diaminobutyric acid; Ac-L-Dab(Boc)-OH; N-Acetyl-N'-Boc-L-2,4-diaminobutyric acid; (2S)-2-Acetamido-4-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid; Boc-Dab(Ac)-OH; Fmoc-Dab(Boc)-OH precursor; L-Dab(Boc)-AcOH; Protected L-Diaminobutyric Acid Derivative
EINECS	Contact for details

Quality Control

Our Ac-Dab(Boc)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive applications. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.