Description

Boc-Dl-Tyr(2,6-Dichloro-Bzl)-Oh is a protected tyrosine derivative, specifically designed for advanced peptide synthesis and medicinal chemistry research. This compound is crucial for introducing modified tyrosine residues into peptide chains, enabling the study of structure-activity relationships and the development of novel bioactive molecules. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on peptide-based drug discovery and proteomics research.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key building block for incorporating a protected, halogenated tyrosine analog into custom peptide sequences.
• Medicinal Chemistry Research: For the design and synthesis of peptide mimetics and novel drug candidates targeting various receptors and enzymes.
• Bioconjugation and Probe Development: Useful in creating labeled peptides for diagnostic assays, imaging studies, or affinity purification due to its modifiable aromatic ring.
• Chemical Biology Studies: Employed to investigate protein-protein interactions and post-translational modifications by incorporating non-natural amino acids into proteins.
• Process Development for API Synthesis: Serves as an intermediate in the scalable production of complex peptide Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	Boc-Dl-Tyr(2,6-Dichloro-Bzl)-Oh
CAS No.	201334-88-5
Molecular Formula	C21H23Cl2NO5
Molecular Weight	440.32 g/mol
Synonyms	N-tert-Butoxycarbonyl-3-(2,6-dichlorobenzyloxy)-DL-tyrosine; Boc-Tyr(2,6-DiCl-Bzl)-OH; Boc-DL-Tyrosine(2,6-dichlorobenzyl ether); tert-Butyl (2,6-dichlorobenzyloxy)-DL-phenylalaninate; (RS)-2-[(tert-Butoxycarbonyl)amino]-3-[4-[(2,6-dichlorophenyl)methoxy]phenyl]propanoic acid; DL-Boc-Tyr(2,6-Cl2-Bzl)-OH; Boc-DL-Tyr(2,6-Cl2-Bzl)-OH
EINECS	Contact for details

Quality Control

Our Boc-Dl-Tyr(2,6-Dichloro-Bzl)-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles for the production of pharmaceutical intermediates, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.