Description

(R,R)-2,7-Di-tert-Butyl-9,9-Dimethyl-4,5-Bis(Methylphenylphosphino)Xanthene is a high-value, chiral bisphosphine ligand critical for enabling highly selective asymmetric catalytic transformations. Its significance lies in its ability to induce exceptional enantioselectivity and high catalytic activity in hydrogenation and other key C-C bond-forming reactions, directly impacting the efficiency and purity of advanced chemical synthesis. This product is essential for R&D scientists and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-performance ligands for developing novel chiral intermediates and active pharmaceutical ingredients (APIs).

Application

• Asymmetric hydrogenation of olefins, ketones, and imines for the production of chiral alcohols and amines.
• Key ligand in rhodium- and ruthenium-catalyzed reactions for the synthesis of enantiomerically pure pharmaceutical intermediates.
• Catalyst component in asymmetric C-C cross-coupling reactions and hydroformylation processes.
• Research and development of novel catalytic systems in academic and industrial laboratories.
• Production of specialty fine chemicals and flavors & fragrances requiring high optical purity.
• Process development and scale-up for the manufacture of chiral agrochemicals.

Basic Information

Product Name	(R,R)-2,7-Di-tert-Butyl-9,9-Dimethyl-4,5-Bis(Methylphenylphosphino)Xanthene
CAS No.	201226-88-2
Molecular Formula	C43H56OP2
Molecular Weight	650.86 g/mol
Synonyms	(R,R)-DTBM-SEGPHOS; (R,R)-2,7-Di-tert-butyl-9,9-dimethyl-4,5-bis(diphenylphosphino)xanthene (common misnomer); (R,R)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole derivative; (R,R)-DTBM-SEGPHOS Ligand; (11bR)-4,6-Bis[3,5-di-tert-butyl-4-methoxyphenyl]-2,8-di-tert-butyl-4,6-dihydro-12H-dimethanodibenzo[d,f][1,3,2]dioxaphosphepin; (R,R)-DTBM-MeO-BIPHEP (related structure); SEGPHOS-based ligand; Chiral Xantphos derivative.
EINECS	Contact for details

Quality Control

Every batch of our (R,R)-DTBM-SEGPHOS is manufactured and tested under strict quality management systems to ensure consistent high purity and enantiomeric excess (ee) critical for catalytic performance. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as chiral purity (by HPLC), elemental analysis, and spectroscopic identification (NMR, IR). Our quality commitment aligns with cGMP principles for advanced pharmaceutical applications, ensuring reliable supply and traceability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.