Description

n-tert-Butoxycarbonyl-4-Chloro-2-Trifluoroacetylaniline is a high-purity, advanced pharmaceutical intermediate characterized by its tert-butoxycarbonyl (Boc) and trifluoroacetyl protecting groups. This compound is essential for the synthesis of complex organic molecules, particularly in medicinal chemistry, where it serves as a key building block for active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, particularly those requiring selective amine protection and functionalization.
• API Synthesis: Used as a building block for constructing active pharmaceutical ingredients (APIs) with specific pharmacological activities.
• Agrochemical Research: Serves as a key intermediate in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated and fluorinated structure.
• Peptide Chemistry: Employed in peptide synthesis where the Boc group provides temporary protection for amine functionalities during chain elongation.
• Material Science: Can be utilized in the research and development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Acts as a starting material for synthesizing labeled compounds and molecular probes used in biochemical assays and diagnostic research.

Basic Information

Product Name	n-tert-Butoxycarbonyl-4-Chloro-2-Trifluoroacetylaniline
CAS No.	201218-07-7
Molecular Formula	C₁₃H₁₃ClF₃NO₃
Molecular Weight	323.70 g/mol
Synonyms	4-Chloro-2-(trifluoroacetyl)aniline, N-Boc derivative; 1-(tert-Butoxycarbonylamino)-4-chloro-2-(trifluoroacetyl)benzene; N-Boc-4-chloro-2-trifluoroacetylaniline; 2-Trifluoroacetyl-4-chloroaniline N-Boc derivative; tert-Butyl [4-chloro-2-(trifluoroacetyl)phenyl]carbamate; N-(tert-Butoxycarbonyl)-4-chloro-2-trifluoroacetylaniline; Boc-4-Cl-2-TFA-aniline
EINECS	Contact for details

Quality Control

Our n-tert-Butoxycarbonyl-4-Chloro-2-Trifluoroacetylaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.