Description

Fmoc-Lys(Palmitoyl)-Oh is a specialized, high-purity protected amino acid derivative, essential for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise lipidation to modify peptide properties such as hydrophobicity, cellular uptake, and bioavailability. It is primarily utilized in pharmaceutical R&D for the development of novel peptide-based therapeutics, vaccines, and diagnostic agents, serving the needs of biotech and pharmaceutical industries globally.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled introduction of a palmitoyl (C16) lipid chain onto lysine residues during Fmoc-based peptide assembly.
• Lipopeptide Drug Development: Used to create therapeutic lipopeptides that mimic natural lipoproteins or enhance membrane permeability and stability.
• Vaccine Adjuvant Research: Employed in synthesizing antigenic peptide conjugates to improve immune response and delivery.
• Bioconjugation and Probe Synthesis: Serves as a precursor for creating fluorescently labeled or biotinylated lipidated peptides for cellular imaging and interaction studies.
• Academic and Industrial R&D: A vital reagent in laboratories focused on peptide chemistry, chemical biology, and medicinal chemistry.

Basic Information

Product Name	Fmoc-Lys(Palmitoyl)-Oh
CAS No.	201004-46-8
Molecular Formula	C₄₀H₆₀N₂O₅
Molecular Weight	636.92 g/mol
Synonyms	Fmoc-Lys(Palmitoyl)-OH; Fmoc-Lys(Palm)-OH; Nα-Fmoc-Nε-palmitoyl-L-lysine; Fmoc-Lys(C16)-OH; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-6-palmitamidohexanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N'-palmitoyl-L-lysine; Fmoc-L-lysine(N-palmitoyl)-OH; Fmoc-Lys(Palmitic acid)-OH
EINECS	Contact for details

Quality Control

Every batch of Fmoc-Lys(Palmitoyl)-Oh is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing results from HPLC, NMR, and mass spectrometry. Our production adheres to cGMP guidelines where applicable, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.