Description

2-Bromo-1-isopropoxy-4-(trifluoromethyl)benzene is a high-value, multi-functional aromatic building block designed for advanced synthetic chemistry. Its unique structure, featuring both bromine and trifluoromethyl substituents on an isopropoxybenzene core, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, contributing to the molecular framework of liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to form complex biaryl structures.
• Functional Polymer Monomer: Incorporated into specialty polymers to impart unique properties such as chemical resistance, thermal stability, and specific optical characteristics.
• Organic Synthesis & Medicinal Chemistry: A versatile reagent for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.

Basic Information

Product Name	2-Bromo-1-isopropoxy-4-(trifluoromethyl)benzene
CAS No.	200956-54-3
Molecular Formula	C10H10BrF3O
Molecular Weight	283.09 g/mol
Synonyms	1-Bromo-2-isopropoxy-5-(trifluoromethyl)benzene; 2-Bromo-1-isopropoxy-4-(trifluoromethyl)benzene; 2-Bromo-α,α,α-trifluoro-p-isopropoxytoluene; Benzene, 2-bromo-1-isopropoxy-4-(trifluoromethyl)-; 4-Trifluoromethyl-2-bromo-1-isopropoxybenzene; Isopropyl 2-bromo-4-(trifluoromethyl)phenyl ether
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-isopropoxy-4-(trifluoromethyl)benzene is manufactured under strict quality management systems. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your internal quality standards and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider using an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.