Description

2-Bromo-1-Ethoxy-4-(Trifluoromethoxy)Benzene is a high-purity halogenated aromatic ether building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industrial researchers and process chemists need it for constructing active pharmaceutical ingredients (APIs), liquid crystal materials, and functional agrochemicals where the introduction of bromine and trifluoromethoxy substituents is critical.

Application

• Pharmaceutical Intermediate: A versatile building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies (LCDs).
• Organic Electronic Materials: Employed in the development of organic semiconductors and charge-transport materials due to its electron-deficient aromatic system.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form complex biaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on fluoroorganic chemistry and new synthetic methodologies.

Basic Information

Product Name	2-Bromo-1-Ethoxy-4-(Trifluoromethoxy)Benzene
CAS No.	200956-50-9
Molecular Formula	C9H8BrF3O2
Molecular Weight	285.06 g/mol
Synonyms	1-Bromo-2-ethoxy-4-(trifluoromethoxy)benzene; 2-Bromo-1-ethoxy-4-(trifluoromethoxy)benzene; 2-Bromo-4-(trifluoromethoxy)phenetole; 1-Ethoxy-2-bromo-4-(trifluoromethoxy)benzene; Benzene, 2-bromo-1-ethoxy-4-(trifluoromethoxy)-; 4-(Trifluoromethoxy)-2-bromophenetole
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Ethoxy-4-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with lot-specific data are provided to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.