Description

1-(Benzyloxy)-4-(2,2,2-trifluoroethoxy)benzene is a high-purity, specialty aromatic ether compound featuring both benzyloxy and trifluoroethoxy functional groups. This unique structure makes it a valuable advanced intermediate for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development teams working on novel active ingredients, where its fluorine-containing moiety can impart desirable metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoroethoxy group can enhance lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor or core structure in the development of specialty chemicals for electronic displays and organic light-emitting diodes due to its aromatic and ether linkages.
• Polymer Science: Potential monomer or modifier for creating specialty polymers with specific thermal or chemical resistance properties.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and other catalytic processes for constructing complex aromatic ethers in academic and industrial research.

Basic Information

Product Name	1-(Benzyloxy)-4-(2,2,2-Trifluoroethoxy)Benzene
CAS No.	200956-20-3
Molecular Formula	C15H13F3O2
Molecular Weight	282.26 g/mol
Synonyms	4-(Benzyloxy)-1-(2,2,2-trifluoroethoxy)benzene; Benzene, 1-(benzyloxy)-4-(2,2,2-trifluoroethoxy)-; 1-(Benzyloxy)-4-(2,2,2-trifluoroethoxy)benzene; p-(Benzyloxy)phenyl 2,2,2-trifluoroethyl ether; 4-(2,2,2-Trifluoroethoxy)phenyl benzyl ether
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for research and production use. Our standard grade for 1-(Benzyloxy)-4-(2,2,2-trifluoroethoxy)benzene typically meets a purity specification of ≥97% (by HPLC), with stringent control of related substances. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.