Description

2-Bromo-1-Methoxy-4-(Trifluoromethoxy)Benzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring bromine and trifluoromethoxy substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting novel small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of specialty chemicals for electronic applications, including liquid crystal displays and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to form new carbon-carbon bonds.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and functionalized aromatics with specific properties.
• Chemical Library Development: A valuable building block for combinatorial chemistry and the generation of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	2-Bromo-1-Methoxy-4-(Trifluoromethoxy)Benzene
CAS No.	200956-14-5
Molecular Formula	C8H6BrF3O2
Molecular Weight	271.04 g/mol
Synonyms	1-Bromo-2-Methoxy-5-(Trifluoromethoxy)Benzene; 2-Bromo-1-Methoxy-4-(Trifluoromethoxy)Benzene; 2-Bromo-4-(Trifluoromethoxy)Anisole; 2-Bromoanisole-4-trifluoromethyl Ether; 4-Trifluoromethoxy-2-Bromoanisole; 5-(Trifluoromethoxy)-2-Bromoanisole; Benzene, 2-bromo-1-methoxy-4-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Methoxy-4-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.