Description

Acetamide, n-Methyl-n-(2,2,2-Trifluoro-1-thioxoethyl)- is a specialized fluorinated thioamide derivative, a key building block in advanced organic synthesis. This compound matters for its unique trifluoromethylthio moiety, which is highly sought after for modulating the physicochemical properties of target molecules, particularly in enhancing metabolic stability and lipophilicity. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethylthio group can improve biological activity and environmental profile.
• Material Science Research: Serves as a precursor for novel fluorinated polymers and liquid crystals with specific optical and electronic properties.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme mechanisms and protein functions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring the introduction of a -SCF3 group into complex molecular architectures.

Basic Information

Product Name	Acetamide, n-Methyl-n-(2,2,2-Trifluoro-1-thioxoethyl)-
CAS No.	200802-71-7
Molecular Formula	C5H6F3NOS
Molecular Weight	185.17 g/mol
Synonyms	N-Methyl-N-[(trifluoromethyl)thio]acetamide; N-Methyl-N-(trifluoromethylthio)acetamide; 2,2,2-Trifluoro-N-methyl-N-(thioxomethyl)acetamide; Acetamide, N-methyl-N-[(trifluoromethyl)thio]-; N-Methyl-N-(trifluoromethylsulfanyl)acetamide; TFTMA; Methyl(trifluoromethylthio)acetamide
EINECS	Contact for details

Quality Control

Our Acetamide, n-Methyl-n-(2,2,2-Trifluoro-1-thioxoethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to fluoride and strong alkali; ensure it is stored separately from such materials. Keep container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.