Description

H-Glu(o-Chloroanilide)-Oh is a specialized chiral amino acid derivative, specifically an anilide of glutamic acid. This compound serves as a critical building block and intermediate in advanced organic synthesis, enabling the precise construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptidomimetics, enzyme inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Peptidomimetic Research: Essential building block for designing and synthesizing peptide analogs with enhanced stability and bioavailability.
• Protease Inhibitor Development: Used in the creation of specific inhibitors targeting enzymes like glutamyl proteases.
• Chemical Biology Probes: Employed in the synthesis of labeled or tagged molecules for studying biological pathways and protein interactions.
• Asymmetric Synthesis: Chiral template for constructing stereochemically defined molecules in medicinal chemistry.
• Academic & Industrial R&D: Serves as a standard or starting material in method development and discovery chemistry projects.

Basic Information

Product Name	H-Glu(o-Chloroanilide)-Oh
CAS No.	200616-97-3
Molecular Formula	C11H13ClN2O3
Molecular Weight	256.69 g/mol
Synonyms	L-Glutamic acid N-(2-chlorophenyl)amide; (S)-2-Amino-5-((2-chlorophenyl)amino)-5-oxopentanoic acid; N2-(2-Chlorophenyl)-L-glutamine; H-Glu(2-Cl-Ph-NH)-OH; o-Chloroanilide of L-Glutamic Acid; Glutamic acid-(2-chloroanilide); N-(2-Chlorophenyl)-L-glutamine
EINECS	Contact for details

Quality Control

Our H-Glu(o-Chloroanilide)-Oh is manufactured under controlled conditions to ensure high chemical purity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and optical rotation analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and chiral integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.