Description

Leptin (150-167) (Human) CAS NO 200436-46-0 is a specific, bioactive fragment of the human leptin hormone, corresponding to amino acid residues 150-167. This synthetic peptide is of significant interest for its role in metabolic research and as a critical tool for studying leptin receptor interactions and signaling pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in endocrinology, obesity, and diabetes research.

Application

• Biochemical Research: Used as a reference standard and active agent in studies investigating leptin's structure-activity relationships, particularly the receptor-binding domain.
• Pharmaceutical Development: Serves as a key intermediate or tool compound in the discovery and screening of novel therapeutics targeting metabolic disorders.
• Cell Signaling Studies: Applied in in vitro assays to stimulate leptin receptors and study downstream JAK-STAT and other signaling cascades.
• Antibody Production: Acts as an immunogen for generating specific antibodies against the leptin protein for diagnostic or research purposes.
• Academic Research: Fundamental tool for university and institutional labs focusing on endocrinology, adipokine biology, and energy homeostasis.

Basic Information

Product Name	Leptin (150-167) (Human)
CAS No.	200436-46-0
Molecular Formula	C94H147N27O26S
Molecular Weight	2099.4 g/mol
Synonyms	Human Leptin Fragment 150-167; Leptin (150-167); OB Peptide (150-167); Leptin Human (150-167); hLEP (150-167); Leptin 150-167 amide; LEP (150-167) Human; Anti-Obesity Hormone Fragment
EINECS	Contact for details

Quality Control

Our Leptin (150-167) (Human) is manufactured under stringent conditions to ensure high purity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical techniques including HPLC, MS, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, identity, and peptide content is provided with each batch to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This hygroscopic and easily oxidized peptide should be handled under inert atmosphere when possible and allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.