Description

Fmoc-L-Isoasparagine CAS NO 200335-40-6 is a protected amino acid derivative specifically engineered for solid-phase peptide synthesis (SPPS). This high-purity building block is critical for the controlled introduction of the isoasparagine residue, enabling the synthesis of complex peptides and peptidomimetics with precise stereochemistry. It is an essential reagent for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require reliable, high-quality intermediates for constructing novel bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): Primary use as a key building block for the Fmoc-strategy synthesis of peptides containing isoasparagine.
• Pharmaceutical Research & Development: Critical intermediate in the discovery and development of peptide-based therapeutics, vaccines, and diagnostic agents.
• Bioconjugation: Used to incorporate specific functional handles into peptides for labeling or coupling with other biomolecules.
• Combinatorial Chemistry: A valuable component in libraries for high-throughput screening to identify new lead compounds.
• Academic Research: Fundamental reagent for studying protein structure, function, and peptide folding mechanisms.
• Synthesis of Peptidomimetics: Employed in creating modified peptide analogs with enhanced stability or biological activity.

Basic Information

Product Name	Fmoc-L-Isoasparagine
CAS No.	200335-40-6
Molecular Formula	C19H18N2O6
Molecular Weight	370.36 g/mol
Synonyms	Fmoc-L-iso-Asn-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoasparagine; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-carbamoylpropanoic acid; Fmoc-L-β-Asparagine; Fmoc-isoAsp-OH; Nα-Fmoc-L-isoasparagine; Fmoc-Asp(β-NH2)-OH; L-Isoasparagine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our Fmoc-L-Isoasparagine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our customers in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.