Description

Z-D-Asn(Trt)-Oh is a protected asparagine derivative widely used as a key building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise stereochemistry. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for the development of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a protected amino acid derivative for the controlled elongation of peptide chains.
• Solution-Phase Peptide Synthesis: For the synthesis of peptides and peptide conjugates in solution.
• Pharmaceutical Intermediate: In the research and development of novel peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: For creating peptide-protein or peptide-small molecule conjugates for targeted therapies.
• Biochemical Research: As a reagent for studying enzyme-substrate interactions and protein folding mechanisms.
• Combinatorial Chemistry: Used in libraries for high-throughput screening to discover new bioactive compounds.

Basic Information

Product Name	Z-D-Asn(Trt)-Oh
CAS No.	200259-87-6
Molecular Formula	C31H28N2O6
Molecular Weight	524.57 g/mol
Synonyms	Nα-Z-Nβ-trityl-D-asparagine; Z-D-Asn(Trt)-OH; N-Benzyloxycarbonyl-N'-trityl-D-asparagine; (2R)-2-[[(Benzyloxy)carbonyl]amino]-3-[(tritylamino)carbonyl]propanoic acid; Z-D-Asparagine(Trt)-OH; CBZ-D-Asn(Trt)-OH; N-CBZ-N'-trityl-D-asparagine; D-Asparagine, N2-[(phenylmethoxy)carbonyl]-N4-(triphenylmethyl)-
EINECS	Contact for details

Quality Control

Our Z-D-Asn(Trt)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Optical Rotation	-10.0° to -14.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.