Description

Boc-D-Asn(Xan)-Oh is a protected amino acid derivative, specifically a xanthyl (Xan)-protected asparagine with a tert-butoxycarbonyl (Boc) group on the α-amino function. This compound is a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, offering precise control over stereochemistry and side-chain reactivity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of D-asparagine into peptide chains, especially where side-chain protection is required.
• Pharmaceutical Research: Used in the research and development of peptide-based drugs, hormones, and enzyme inhibitors.
• Bioconjugation: Serves as a precursor for creating labeled peptides or peptide-protein conjugates for diagnostic and imaging applications.
• Combinatorial Chemistry: Employed in libraries for drug discovery to explore structure-activity relationships (SAR).
• Academic Research: A valuable reagent for studying peptide structure, function, and folding in biochemistry and molecular biology laboratories.

Basic Information

Product Name	Boc-D-Asn(Xan)-Oh
CAS No.	200192-48-9
Molecular Formula	C₁₉H₂₀N₂O₆
Molecular Weight	372.37 g/mol
Synonyms	N-α-(tert-Butoxycarbonyl)-N-β-(9H-xanthen-9-yl)-D-asparagine; Boc-D-Asn(Xan)-OH; (R)-2-((tert-Butoxycarbonyl)amino)-3-((9H-xanthen-9-yl)amino)-3-oxopropanoic acid; Boc-D-Asparagine(Xan)-OH; tert-Butyloxycarbonyl-D-asparagine(xanthyl) acid; BOC-D-ASN(XAN)-OH; D-Asn(Xan)-Boc-OH
EINECS	Contact for details

Quality Control

Our Boc-D-Asn(Xan)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.