Description

Z-D-Arg(Pmc)-Oh Cha is a protected arginine derivative, specifically designed for use in peptide synthesis. This compound is critical for researchers and manufacturers requiring high-purity, chemically defined building blocks to ensure the integrity and reproducibility of complex peptide sequences. It is primarily utilized by the pharmaceutical, biotechnology, and life sciences industries for the research and development of novel therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key protected amino acid building block for the controlled assembly of peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions for constructing specific peptide fragments.
• Pharmaceutical Intermediate: An essential raw material in the research and production of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Facilitates the site-specific modification of proteins or other biomolecules via its reactive functional groups.
• Biochemical Research: Employed in studies of enzyme-substrate interactions, receptor binding, and other structure-activity relationship (SAR) investigations.
• Custom Peptide Service: A fundamental reagent used by CROs and CDMOs for the contract manufacturing of custom peptide sequences.

Basic Information

Product Name	Z-D-Arg(Pmc)-Oh Cha
CAS No.	200191-08-8
Molecular Formula	C31H44N6O7S
Molecular Weight	644.79 g/mol
Synonyms	Nα-Z-Nω-(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-D-arginine Cyclohexylammonium Salt; Z-D-Arg(Pmc)-OH·CHA; Z-D-Arg(Pmc)-OH Cyclohexylamine; Benzyloxycarbonyl-Nω-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-D-arginine Cyclohexylammonium Salt; D-Arg(Z,Pmc)-OH·CHA; Boc-D-Arg(Pmc)-OH·CHA (common analog); Fmoc-D-Arg(Pmc)-OH·CHA (common analog); Protected D-Arginine derivative
EINECS	Contact for details

Quality Control

Our Z-D-Arg(Pmc)-Oh Cha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for peptide synthesis. Certificates of Analysis (COA) with full traceability are provided to guarantee consistent quality and batch-to-batch reproducibility for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.