Description

Di-T-Butyl(n-Butyl)Phosphine is a high-purity, sterically hindered tertiary phosphine ligand, a critical component in advanced catalytic systems. Its primary value lies in its ability to facilitate highly efficient and selective cross-coupling reactions, which are fundamental to modern organic synthesis. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds and optimize manufacturing processes.

Application

• As a key ligand in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Buchwald-Hartwig aminations.
• Enabling the synthesis of complex pharmaceutical intermediates and active ingredients (APIs) under mild conditions.
• Catalyst component for the production of agrochemicals, fine chemicals, and advanced materials.
• Used in academic and industrial research for developing new catalytic methodologies.
• Facilitates polymerization catalysis for creating specialized polymers.
• Employed in asymmetric synthesis when used with chiral metal complexes.

Basic Information

Product Name	Di-T-Butyl(n-Butyl)Phosphine
CAS No.	29949-72-2
Molecular Formula	C12H27P
Molecular Weight	202.32 g/mol
Synonyms	Di-tert-Butyl(n-butyl)phosphine; Di-tert-butylbutylphosphine; (Butyl)di-tert-butylphosphine; DTBBP; t-Bu2P(n-Bu); Phosphine, di-tert-butylbutyl-; Ligand for cross-coupling
EINECS	Contact for details

Quality Control

Our Di-T-Butyl(n-Butyl)Phosphine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, GC, and titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material must be stored and handled under an inert atmosphere (argon or nitrogen). Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizers and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.