Description

Z-Dl-Asp(Obzl)-Oh is a protected aspartic acid derivative, specifically the benzyl ester of N-carbobenzoxy-DL-aspartic acid. This compound is a crucial chiral building block and intermediate in sophisticated organic synthesis, particularly for the construction of peptides and peptidomimetics. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, well-defined intermediates for drug discovery and development processes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate aspartic acid residues with protected side chains.
• Bioconjugation & Linker Chemistry: Serves as a precursor for creating specialized linkers or modifying biomolecules due to its reactive carboxylic acid and protected amine functionalities.
• Research & Development: A valuable tool in academic and industrial R&D for studying enzyme inhibitors, receptor ligands, and other bioactive peptides.
• Fine Chemical Synthesis: Intermediate in the multi-step synthesis of complex organic molecules requiring chiral amino acid components.

Basic Information

Product Name	Z-Dl-Asp(Obzl)-Oh
CAS No.	29880-21-5
Molecular Formula	C19H19NO6
Molecular Weight	357.36 g/mol
Synonyms	N-Carbobenzoxy-DL-aspartic acid β-benzyl ester; Z-DL-Aspartic acid β-benzyl ester; Z-Asp(OBzl)-OH, DL-; N-(Benzyloxycarbonyl)-DL-aspartic acid 4-benzyl ester; Benzyl N-(benzyloxycarbonyl)-DL-aspartate; DL-2-[[(Benzyloxy)carbonyl]amino]butanedioic acid 4-benzyl ester; Z-DL-Asp(OBzl)-OH; N-Cbz-DL-aspartic acid β-benzyl ester
EINECS	Contact for details

Quality Control

Our Z-Dl-Asp(Obzl)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data, including HPLC purity, chiral purity, and residual solvent analysis, meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	DL-mixture (approx. 1:1 ratio)
Loss on Drying	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.