Description

Meconin-D3 CAS NO 29809-15-2 is a deuterium-labeled isotopologue of meconin, a naturally occurring lactone. This stable isotope-labeled compound is an essential tool for analytical research, providing a critical internal standard for precise quantification. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, forensic, and metabolomic fields.

Application

• Internal Standard for Mass Spectrometry (MS): Essential for accurate quantification of meconin and related compounds in complex biological matrices using LC-MS/MS and GC-MS.
• Pharmaceutical Research & Development: Used in pharmacokinetic (PK) and drug metabolism studies to track the absorption, distribution, metabolism, and excretion (ADME) of meconin or its derivatives.
• Forensic Toxicology: Serves as a reference standard for the detection and confirmation of opiate alkaloids or their metabolites in forensic analyses.
• Metabolomics & Biomarker Discovery: Enables precise measurement of endogenous meconin levels in metabolic pathway studies and biomarker validation.
• Method Development & Validation: Critical for developing and validating robust, high-precision analytical methods in compliance with regulatory guidelines (e.g., FDA, ICH).
• Quality Control (QC) in Reference Material Production: Used to certify and ensure the accuracy of unlabeled meconin reference standards.

Basic Information

Product Name	Meconin-D3
CAS No.	29809-15-2
Molecular Formula	C10H7D3O4
Molecular Weight	197.20 g/mol
Synonyms	6,7-Dimethoxy-2H-1-benzopyran-2-one-d3; 6,7-Dimethoxycoumarin-d3; 3,4-Dimethoxycoumarin-d3; 6,7-Dimethoxy-2-oxo-2H-chromene-d3; 6,7-Dimethoxy-2H-chromen-2-one-d3; Opianic acid lactone-d3; NSC 407337-d3
EINECS	Contact for details

Quality Control

Our Meconin-D3 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Each batch is accompanied by comprehensive analytical data, including NMR (Nuclear Magnetic Resonance) and MS (Mass Spectrometry) for isotopic enrichment verification, and HPLC for chemical purity. A detailed Certificate of Analysis (COA) is provided, confirming compliance with our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 99.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.