Description

1-(4-Methoxyphenyl)Cyclobutanecarbonitrile is a versatile organic nitrile building block featuring a cyclobutane ring and a methoxyphenyl substituent, offering a unique structural motif for advanced chemical synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), fine chemicals, and novel material precursors.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring cyclobutane-based scaffolds for enhanced metabolic stability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the 4-methoxyphenyl and nitrile functionalities impart specific biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing advanced organic electronic materials due to its rigid-rod-like molecular structure and potential for functionalization.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialty chemicals, flavors, and fragrances.
• Academic & Industrial R&D: Utilized in methodological studies, such as ring-opening reactions or catalytic transformations of strained rings, to explore new synthetic pathways.

Basic Information

Product Name	1-(4-Methoxyphenyl)Cyclobutanecarbonitrile
CAS No.	29786-45-6
Molecular Formula	C12H13NO
Molecular Weight	187.24 g/mol
Synonyms	4-(Cyclobutanecarbonitrile)anisole; p-Methoxyphenylcyclobutanecarbonitrile; 1-(4-Methoxyphenyl)cyclobutanecarbonitrile; 1-(p-Methoxyphenyl)cyclobutanecarbonitrile; Cyclobutanecarbonitrile, 1-(4-methoxyphenyl)-; 4-(1-Cyanocyclobutyl)anisole; 1-(4-Methoxyphenyl)cyclobutane-1-carbonitrile
EINECS	Contact for details

Quality Control

Our 1-(4-Methoxyphenyl)Cyclobutanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.